Concomitant administration of duloxetine 40 mg twice daily with fluvoxamine 100 mg, a potent cyp1a2 inhibitor, to cyp2d6 poor metabolizer subjects n 14 resulted in a 6-fold increase in duloxetine auc and c max.
Concomitant administration of duloxetine 40 mg twice daily with fluvoxamine 100 mg, a potent cyp1a2 inhibitor, to cyp2d6 poor metabolizer subjects n 14 resulted in a 6-fold increase in duloxetine auc and c max.
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